An update on corneal hydration control

Exp Eye Res. 2004 Mar;78(3):537-41. doi: 10.1016/j.exer.2003.09.010.

Abstract

An account is provided of developments in our understanding of the mechanism of corneal hydration control, particularly as regards the possibility of an active system for its regulation. Emphasis is given to issues that are contentious, such as the role of bicarbonate in the endothelial pump and the significance of water channels in both corneal limiting cell layers.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Anion Transport Proteins / physiology
  • Bicarbonates / metabolism
  • Body Water / metabolism*
  • Cell Membrane Permeability / physiology
  • Cornea / metabolism*
  • Endothelium, Corneal / metabolism
  • Epithelium, Corneal / metabolism
  • Humans

Substances

  • Anion Transport Proteins
  • Bicarbonates